Dr. David Dilley Distinguished Professor A34 Plant and Soil Sciences Michigan State University East Lansing, MI 48824-1325 Phone: 517/355-5191, ext 308 Fax: 517/353-0890 Email: dilley@msu.edu

Education:

Ph.D., Plant Physiology, N. Carolina State University, 1960

M.S., Horticulture, Michigan State University, 1957

B.S., Agriculture, Michigan State University, 1955

Professional Experience:

Michigan State University
Assistant Professor, 1960-64
Associate Professor, 1964-67
Professor, 1967 to 1992
Distinguished Professor 1992-date

Sabbatical Leaves: 1969, Plant Research Lab, Fairchild Garden, Miami; 1983, Dept. of Chemistry, Imperial College Sci. & Tech., London UK; 1990, University of W. Sydney, Hawkesbury, Australia; 1998, Massey University, Palmerston North, New Zealand; consultant to numerous corporations in handling transportation and storage of perishables.

Research Interests:

Physiology and biochemistry of fruits, vegetables, and flowers in relation to maturation, ripening, senescence and postharvest preservation. Handling, transportation, and storage of perishable horticultural commodities. Instrument design for gas analyzers: ethylene, oxygen and carbon dioxide. Air purification and separation equipment design and application for controlled atmosphere storage of perishables. Enzymology and molecular biology of ethylene biosynthesis and ethylene action in gene expression of ripening.

Honors and Awards:

• Alpha Zeta 1954
• Sigma Xi 1956
• Dow Chemical Award-American Society for Horticultural Science, 1970
• Fellow - American Society of Horticultural Science, 1977
• Distinguished Graduate Teaching Award, American Society of Horticultural Science, 1981
• Excellence in Research Award - The Grower 1986
• Fellow - American Association Advancement of Science, 1989
• Fellow - University of Western Sydney, 1990
• Distinguished Faculty Award, Michigan State University, 1992
• Distinguished Service Award, Michigan State Horticultural  Society, 1995
• Fruit Man of the Year Award - 1999, Michigan State Association of Pomester Clubs.

• Dilley, D.R., Wang, Z and Kadyrzhanova, D.K. 2003. Mechanism of bicarbonate and ascorbic acid activation of 1-aminocyclopropane-1-carboxylate (ACC) oxidase. Biology and Biotechnolgy of the Plant Hormone Ethylene III. M. Vendrell et al. (Eds.). IOS Press, pp 9-14.
• Golding, J.B., Wang, Z. and Dilley, D.R. 2003. Role alcohol dehydrogenase in preventing superficial scald in apples. Proc. 8^th Int’l. Controlled Atmosphere Conference. Eds. J. Oosterhaven and H.W. Peppelenbos, Acta Horticultrae 600:267-269.
• Golding, J.B., Wang, Z. and Dilley, D.R. 2003. Effects of 1-methylcyclopropene and light on postharvest color development in apples. Proc. 8^th Int’l. Controlled Atmosphere Conference. Eds. J. Oosterhaven and H.W. Peppelenbos, Acta Horticultrae 600:85-87.
• Wang, Z. and Dilley, D.R. 2001. Aminoethoxyvinylglycine, combined with ethephon, can enhance red color development without over-ripening apples. HortScience. 36:328-331.
• Dilley, D.R., Kadyrzhanova, D. and Wang. Z. 2001. Mechanism of carbon dioxide activation of 1- aminocyclopropane-1-carboxylate(ACC) oxidase. Acta Horticulturae 553:143-144..
• Wang, Z and Dilley, D.R. 2001. Initial low oxygen stress controls scald of apples without postharvest chemical treatments. Acta Horticulturae 553:261-266.
• Vlachonasios, K., Kadyrzhanova, D.K. and Dilley, D.R. 2001. Heat treatment prevents chilling injury of tomato fruits: Involvement of heat shock genes and and heat shock proteins in the resistance of tomato fruit to low temperatures. Acta Horticulturae 553:543-547.
• Wang, Z. and Dilley, D.R. 2001. ReTain (AVG), combined with ethephon, can enhance red color development without over-ripening apples. Proc. Mich. State Hort. Soc. 130:123-130.
• Wang, Z. and Dilley, D.R. 2000. Hypobaric storage reveals the nature of low temperature induction of superficial scald of apples. Postharvest Biol. Technol. 18:191-199.
• Wang, Z. and Dilley, D.R. 2000. Enhancing red color development without over-ripening apples by ReTain^TM followed by ethephon treatment. Proc. Mich. State Hort. Soc. 129:211-217.
• Wang, Z., Kosittrakun, M. and Dilley, D.R. 2000. Temperature and atmosphere regimens to control a CO₂-linked disdorder of ‘Empire’ apples. Postharvest Biol. Tech. 18:183-189.
• Wang, Z. and Dilley, D.R. 2000. Initial low oxygen stress controls superficial scald of apples. Postharvest Biol. Tech. 18:201-213.
• Dilley, D.R. and Wang, Z. 1999. Enhancing red color development without over-ripening apples by ReTain^TM followed by ethephon treatment. Proc. Mich. State Hort. Soc. 129:211-217.
• Wang, Z and Dilley, D.R. 1999. Control of superficial scald of apples by low-oxygen atmospheres. HortScience 34:1145-1151.
• Kadyrzhanova, D., McCully, T., Warner, T., Vlachonasios, K., Wang, Z. and Dilley, D.R. 1999. Analysis of ACC oxidase by site-directed mutagenesis of conserved amino acid residues. In: Kanellis, A.K. (ed.), Biology and Biotechnology of the Plant Hormone Ethylene II. Kluwer Academic Publ., Dordrecht, The Netherlands. pp 7-12.
• Kadyrzhanova, D.K., Vlachonasios, K.E., Ververidis, P. and Dilley, D.R. 1998. Molecular cloning of a novel heat-treatment/cold tolerance related cDNA in tomato fruit: Use of mRNA differential display. Plant Mol. Biol. 36:885-895.
• Wang, Z. and Dilley, D.R. 1997. The relationship of α-farnesene production and its oxidation product 6-methyl-5-heptene-2-one to superficial scald of Granny Smith, Law Rome, Red Delicious and Idared apples during controlled atmosphere and air storage. Proc. 7th International CA Conference. 2:98-104.
• Wang, Z., T.J. McCully and D.R. Dilley. 1997. The effect of ultra low oxygen storage, initial oxygen stress and ethnol vapor treatments on controlling superficial scald of Granny Smith, Law Rome, Red Delicious and Idared apples. Proc. 7th International CA Conference. 2:105-111.
• Kadyrzhanova, D.K., Ververidis, P., McCully, T.J., Jaworski, S.A., Vlachonasios, K.E., Murakami, K.G.and Dilley, D.R. 1997. Structure-function analysis of ACC oxidase by site-directed mutagenesis. In: Kanellis, A.K. (Ed), Biology and Biotechnology of the Plant Hormone Ethylene. Kluwer Academic Publ., Dordrecht, Netherlands. pp. 5-13.
• Vlachonasios, K., Kadyrzhanova, D.K. and Dilley, D.R. 1996. A heat-treatment chilling tolerance related cDNA from tomato fruit encoding a small heat-shock protein class II LE 17.6 (Accession number U72396) GenBank Data Base.
• Kuai, J., Pekker, Y., Burmeister, D.M., Beaudry, R.M. and Dilley, D.R. 1995. Induction of 1-aminocyclopropane-1-carboxylate (ACC) oxidase during maturation and ripening of apple fruit. In: Postharvest Physiology, Pathology and Technologies for Horticultural Commodities-Recent Advances. Eds. Ait-Oubahou, A. and El-Otmani, M. Institut Agronomique and Veternaire Hassan II, Agadir, Morocco. p. 313-323.
• Burmeister, M. and Dilley, D.R. 1995. A `scald-like' controlled atmosphere storage disorder of Empire apples- a chilling injury induced by CO₂. Postharvest Biol. and Technol. 6:1-7.
• Dilley, D.R., Burmeister, D.M., Beaudry, R.M., Abouzied, M. and Miller, B. 1995. Development of an ACC oxidase ELISA to assess fruit maturity. Proc. 22nd Ann. Mtg. Plant Growth Regul. Soc. Amer. 1995:175-182.
• Ververidis, P. and Dilley, D.R. 1995. Catalytic-and non-catalytic inactivation of 1-aminocyclopropane-1-carboxylate (ACC) oxidase in ethylene biosynthesis: role of cyanide product. Proc. 22nd Ann. Mtg. Plant Growth Regulation Society America 1995:183-199.
• Dilley, D.R., Kuai, J., Wilson, I.D., Pekker, Y., Zhu, Y. Burmeister, D.M., and Beaudry, R.M. 1995. Molecular biological investigation of ACC oxidase and its expression attending apple fruit ripening. Acta Horticulturae 379:25-39.
• Dilley, D.R. Burmeister, D.M., Walker, J.K., Abouzied, M. and Miller, B.M. 1994. Molecular and biochemical aspects of ACC oxidase in ethylene biosynthesis in relation to maturation and ripening of apple fruits. In: Woltering, E.J. et al., Eds., The Postharvest Treatment of Fruits and Vegetables. Proc. 6^th Intl. Symposium COST 94. pp 295-305.
• Burmeister, D.M. and Dilley, D.R. 1994. Correlation of bitter pit on Northern Spy apples with bitter pit-like symptoms induced by Mg²⁺ salt infiltration. Postharvest Biol. Technol. 4:301-308.
• Dilley, D.R., Kuai, J., Poneleit, L., Zhu, Y., Pekker, Y., Wilson, I.D., Burmeister, D.M., Gran, C. and Bowers, A. 1993. Purification and characterization of ACC oxidase and its expression during ripening in apple fruit. In: Cellular and Molecular Aspects of the Plant Hormone Ethylene. Eds. J.C. Pech, A. Latche and C. Balague. Kluwer Academic Publishers, Dordrecht, The Netherlands. pp. 46-52.
• Wilson, I.D., Zhu, Y., Burmeister, D.M. and Dilley, D.R. 1993. The apple ripening-related cDNA clone pAP4 confers ethylene forming ability in transformed Saccharomyces cerevisiae. Plant Physiol. 102:783-788.
• Burmeister, D.M. and Dilley, D.R. 1993. Characterization of Mg²⁺ induced bitter pit-like symptoms on apples: a model system to study bitter pit initiation and development. J. Agric. and Food Chem. 41:1203-1207.
• Poneleit, L.S. and Dilley, D.R. 1993. Carbon dioxide activation of 1-aminocyclopropane-1-carboxylate (ACC) oxidase in ethylene biosynthesis. Postharvest Biol. and Technol. 3:191-199.
• Kuai, J. and Dilley, D.R. 1992. Extraction, partial purification and characterization of 1-aminocyclopropane-1-carboxylic acid oxidase from apples (Malus domestica L). Postharvest Biol. Tech. 1:203-211.
• Ye, W. and Dilley, D.R. 1992. Development of ACC oxidase activity during maturation and ripening of ‘PaulaRed’, ‘Empire’ and ‘Law Rome’ apples. Postharvest Biol. Tech. 1:195-201.
• Dilley, D.R. and Wilson, I.D. 1992. Molecular biological investigations of gene expression attending fruit ripening. Hort Technol. 2:294-301.
• Jobling, J., McGlasson, W.B and Dilley, D.R. 1991. Induction of ethylene synthesizing competency in Granny Smith apples by exposure to low temperature in air. Postharvest Biol. Tech. 1:111-118.
• Burmeister , D.M. and Dilley, D.R. 1991. Induction of bitterpit-like symptoms on apples by infiltration with Mg⁺² is attenuated by Ca⁺² . Postharvest Biol. Tech. 1:11-17.
• Tomala, K. and Dilley, D.R. 1990. Some factors influencing the calcium level in apple fruits. Acta Horticulturae 274:481-487.
• Dilley, D.R. 1990. Historical aspects and perspectives of controlled atmosphere storage. In: Food Preservation by Modified Atmospheres. Caldron, M. and Barki-Golan, R.(Eds.) CRC Press, Inc. Boston, MA. pp187-196.
• Dilley, D.R. 1990. Air separator technology development for controlled atmosphere storage. In: Fellman, J. (Ed.), Proc. 5^th Intl. Controlled Atmosphere Res. Conf., Wenatchee, WA.. pp 409-418.
• Dilley, D.R., Lange, E. and Tomala, K. 1990. Optimizing parameters for controlled atmosphere storage of apples. In: Fellman, J (Ed.), Proc. 5^th Intl. Controlled Atmosphere Res. Conf., Wenatchee, WA. pp 221-236.
• Tomala, K. and Dilley, D.R. 1990. Calcium content of McIntosh and Spartan apples is influenced by the number of seeds per fruit. In: Fellman, J (Ed.), Proc. 5^th Intl. Controlled Atmosphere Res. Conf., Wenatchee, WA. pp 75-81.

Patents:

U.S. Patent No. 4, 410, 632.  Gas Sensing Apparatus and Method. Dilley, D.R., Saltveit,  M.E., and Lee, J.  10/18/83.

U.S. Patent No. 4, 414, 839. Gas Sensing Apparatus and Method.  Dilley, D.R., Saltveit, M.E., and Lee, J. 11/15/83.

U.S. Patent No. 6,284,483. Modified Synthetases to Produce Penicillins and Cephalosporins under  Control by Bicarbonate.  Dilley, D.R., Kadyrzhanova, D.K, Wang, Zhenyong and Warner, T.M.. 9/5/01.